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WT1 is a transcriptional regulator with multifaceted roles in development, tissue homeostasis, and disease pathogenesis [48]

Having overweight or obesity can contribute to hormonal imbalances, insulin resistance, chronic inflammation, and altered reproductive hormone signaling, all of which may impair fertility

Body Composition: GH replacement in GHD adults increases lean mass by 35 kg and decreases fat mass by 34 kg over 12 months, with preferential reduction of visceral adipose tissue

This is due to research showing how a diet that is low in glycaemic load can help stabilise blood sugar levels and therefore help optimise brain function